Circulating microRNA expression is reduced in chronic kidney disease
نویسندگان
چکیده
منابع مشابه
Circulating microRNA expression is reduced in chronic kidney disease.
BACKGROUND MicroRNAs (miRNAs) are important regulators of gene expression, which have roles in renal development and disease. They exist in biological fluids including blood and urine and may have signalling roles and potential as disease biomarkers. METHODS We measured the levels of miRNAs in patients with different stages of chronic kidney failure including those receiving maintenance haemo...
متن کاملCirculating Endoglin Concentration Is Not Elevated in Chronic Kidney Disease
BACKGROUND Soluble endoglin, a TGF-β receptor, plays a key role in cardiovascular physiology. Whether circulating concentrations of soluble endoglin are elevated in CKD or underlie the high risk of cardiovascular death associated with chronic kidney disease (CKD) is unknown. METHODS Individuals with and without CKD were recruited at a single center. Estimated glomerular filtration rate (eGFR)...
متن کاملEndocrine disorders in chronic kidney disease
Background and Objective: Endocrine disorders are common in patients with chronic kidney disease (CKD). The aim of the present study is reviewing available literature to give a deep understanding of complexities of endocrine disorders in chronic kidney disease. Methods: A narrative reviewing method based on the available literature was approached. Findings: Generally, when renal function de...
متن کاملCirculating Endothelial Cells and Chronic Kidney Disease
Endothelial dysfunction may play a crucial role in initiation of the pathogenesis of vascular disease and atherosclerosis. The identification and quantification of circulating endothelial cells (CEC) have been developed as a novel marker of endothelial function. We describe, in great detail, mechanisms of endothelial dysfunction and CEC detachment. We also review the relationship between number...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nephrology Dialysis Transplantation
سال: 2011
ISSN: 1460-2385,0931-0509
DOI: 10.1093/ndt/gfr485